World Down Syndrome Day, March 21, is a global awareness day which has been officially observed by the United Nations since 2012. On this day, people with Down syndrome and those who live and work with them throughout the world organize and participate in activities and events to raise public awareness and create a single global voice for advocating for the rights, inclusion and well-being of people with Down syndrome.

The date for World Down Syndrome Day is the 21st day of the 3rd month, which was selected to signify the uniqueness of the triplication (trisomy) of the 21st chromosome which causes Down syndrome.

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